Hendrick Goltzius, c.1600, pen and ink on paper. Originally from the collection of Emperor Rudolph II.
Although crippled as a child, his hand mutilated by a fireplace accident, Hendrick Goltzius became a preeminent graphic artist of his era (a painter, too, his oils are less than mediocre comparing to his works on paper). Here he portrays his unfortunate extremity, which also happens to be a bodily part of utmost importance to his 'trade' - the artist's hand. An ultimate self-portrait that tells you more about the author than any possible physiognomic depiction.